Hotel COMFORT INN MISSION VALLEY, 2201 HOTEL CIRCLE SOUTH, United states. The Comfort Inn Old Town/Mission Valley is located 6 miles from San Diego International Airport, and just 1 mile from Old Town San Diego. This newly renovated property offers guests the perfect combination of high quality service and comfortable accommodations at reasonable prices. Guests at the Comfort Inn Mission Valley enjoy the warm, personal service that they received from the best hotels in the world. At Comfort Inn, the staff prides itself in being the best by providing excellent customer service. Each spacious, comfortable guestroom at the Comfort Inn Mission Valley is tastefully decorated in warm, rich colors, with attractive, modern furniture. All guest rooms offer a full range of modern amenities, including such convenient features as electronic door locks, coffee/tea makers with complimentary coffee, and irons with ironing boards. You simply can't go wrong with this hotel. The Comfort Inn Mission Valley is just minutes to fine dining, shopping and entertainment venues.